Medical experts in India are advising vegetarians to monitor their vitamin B12 and homocysteine levels to prevent inflammation and heart disease.
This warning is critical because vitamin B12 is primarily found in animal products, leaving those on plant-based diets more susceptible to deficiencies. When B12 levels drop, the body may experience an increase in homocysteine, a marker closely linked to systemic inflammation and a higher risk of cardiovascular events [1, 2].
Dr. Manjusha Agarwal of Gleneagles Hospital in Mumbai said low B12 levels are now seen almost as a common nutritional gap in India [2]. The deficiency can impact the body's basic functioning, as the vitamin is essential for metabolic processes.
Vitamin B12 helps support energy production and maintain nerve health, according to medical reviewer Patricia Mikula, PharmD [3]. Without adequate levels, individuals may experience fatigue or neurological issues. Dr. Navin Gnanasekaran said the importance of tracking both the vitamin levels and homocysteine is necessary to get a complete picture of cardiovascular health [1].
While some health writers have described B12 as a super supplement that can stave off cognitive decline, doctors said it is a fundamental requirement for daily nutrition rather than an optional boost [4]. For vegetarians, the gap is often filled through fortified foods or supplements, but clinical monitoring remains the only way to ensure levels are sufficient to prevent heart-related risks [1, 2].
Maintaining these levels is particularly important in regions with high populations of vegetarians, where dietary patterns may lead to widespread deficiency if not managed through medical guidance [2].
“Low B12 levels are now seen almost as a common nutritional gap in India.”
The focus on homocysteine alongside B12 indicates a shift toward preventative cardiovascular screening for plant-based populations. Because B12 deficiency is an invisible precursor to inflammation, monitoring these biomarkers allows clinicians to intervene before permanent nerve damage or heart disease occurs, moving beyond simple vitamin supplementation to targeted risk management.



