Unknown thieves stole four Renaissance-era paintings from the MuMe museum in Messina, Sicily, on Saturday evening [1, 2, 3].

The heist represents a significant loss of cultural heritage, as the stolen works include rare panels from a 15th-century masterpiece valued in the millions of euros [4].

Italian officials said four paintings by the Renaissance master Antonello da Messina were taken from the museum on Saturday [1]. Among the stolen pieces were three of the five surviving panels of the 1473 San Gregorio Polyptych [1].

The theft occurred on Aug. 15, 2026 [2]. Local authorities said the crime coincided with regional religious celebrations for the Assumption of the Virgin Mary, which drew large crowds across the town [4].

Investigators said the robbery was a professional hit because the artworks were taken overnight without alarms being triggered [4]. Other reports indicate the thieves bypassed the museum's security systems [1].

Police have not disclosed a motive for the theft, but the estimated value of the missing artworks reaches into the millions of euros [4]. The MuMe museum remains the primary site of the investigation as officials search for the missing panels and the remaining painting.

The works were taken overnight without alarms being triggered, raising suspicion of a professional hit.

The theft of the San Gregorio Polyptych panels highlights a recurring vulnerability in regional Italian museums, where high-value art is often housed in facilities with security systems that can be bypassed by professional syndicates. The timing of the heist during a major religious holiday suggests the perpetrators used the public festivities as a tactical distraction to mask their movements.