Canada will retaliate against tariffs imposed by President Donald Trump on a range of Canadian imports, Minister Dominic LeBlanc said Tuesday.

The dispute marks a significant escalation in trade tensions between the two neighbors following the collapse of recent trade negotiations. The move threatens the stability of one of the world's largest trading relationships.

LeBlanc, the Canadian minister responsible for Canada-U.S. trade, said during an interview on CNBC’s “Squawk Box” program that Canada is taking a proactive stance in response to the new trade barriers.

"We’re not waiting by the phone," LeBlanc said.

The friction follows the implementation of 50% [1] tariffs on various Canadian goods. These measures went into effect after diplomatic efforts to reach a trade agreement failed.

LeBlanc did not specify the exact nature of the Canadian retaliation during the interview, but he said the government would not remain passive. The 50% [1] levy on imports is seen as a primary catalyst for the current standoff.

Trade officials have noted that the collapse of negotiations left little room for compromise. The resulting tariffs impact a wide array of goods moving across the border, a development that has prompted the Canadian government's vow to respond.

"We’re not waiting by the phone."

The collapse of trade negotiations and the subsequent imposition of 50% tariffs signal a shift toward protectionism in North American trade. Canada's commitment to retaliate suggests a move away from diplomatic appeals and toward a reciprocal trade war, which could disrupt supply chains and increase costs for consumers in both nations.