The U.S. Drug Enforcement Administration began the process to temporarily schedule the synthetic opioid 7-OH and three of its derivatives [2].
This action targets a potent substance that has become widely available in retail settings. By placing these compounds under controlled-substance scheduling, the agency aims to remove them from gas-station shelves nationwide [1].
Health officials said that 7-OH is a synthetic opioid derived from kratom. They said that the substance poses a significant risk of addiction and overdose, along with other public-health harms [1]. Because these products were previously legal, they were frequently sold in gummies and other forms at convenience stores [3].
The DEA initiated this scheduling process on July 1, 2024 [1]. The move specifically includes 7-OH and three related synthetic derivatives [2].
Once scheduled, the sale and distribution of these substances would be strictly regulated under federal law. This would effectively end the legal retail availability of the compounds in the gas stations where they were commonly found [1], [2].
The agency is acting to curb the accessibility of synthetic opioids that mimic the effects of more traditional narcotics. By targeting the supply chain at the retail level, the DEA seeks to reduce the number of individuals exposed to these high-potency synthetic compounds [1], [3].
“The DEA began the process to temporarily schedule the synthetic opioid 7-OH and three of its derivatives.”
This move signals a shift in federal strategy to address 'legal' highs that occupy a regulatory gray area. By targeting 7-OH, the DEA is attempting to close a loophole where synthetic derivatives of botanical substances, like kratom, are engineered to bypass existing drug laws while maintaining high potency and addictive properties.



