At least one in four former NFL players who died between 2016 and 2021 had chronic traumatic encephalopathy (CTE) [1].
The findings highlight a persistent risk of degenerative brain disease for athletes in high-impact sports. This data suggests that the prevalence of CTE among professional football players remains significant despite changes to league safety protocols.
The study, published in the British Medical Journal, analyzed the brains of former players who died during a specific five-year window from 2016 to 2021 [2]. Researchers found that approximately 25% of these individuals showed signs of the disease [1].
Chronic traumatic encephalopathy is a progressive brain condition associated with repeated blows to the head. Lead author Daniel Daneshvar said the head knocks that contribute to the disease begin at childhood and occur throughout the players' amateur and professional careers.
According to the researchers, the cumulative effect of these impacts—spanning youth, college, and professional levels—contributes to the development of the condition [1]. The study emphasizes that the damage is not limited to the professional era but is a lifelong progression.
This research adds to a growing body of evidence regarding the long-term neurological risks associated with American football. The results underscore the vulnerability of players to permanent brain damage resulting from the inherent nature of the sport.
“At least one in four former NFL players who died between 2016 and 2021 had CTE.”
The study indicates that CTE is not merely a result of professional-level collisions but a cumulative process starting in youth. By identifying a 25 percent prevalence rate among deceased players, the research suggests that current safety measures may not be sufficient to counteract the damage sustained early in an athlete's life, potentially shifting the focus of injury prevention toward youth and amateur sports.



