Never-married men in the U.S. are more likely to develop cancer than married men, according to a University of Miami study.

The findings suggest that social determinants—including emotional support and financial stability—play a critical role in long-term health outcomes. This indicates that the absence of a spouse may correlate with higher health risks beyond genetic or environmental factors.

Researchers at the University of Miami Miller School of Medicine analyzed data from 12 U.S. states, totaling more than four million cancer cases [4]. The results, reported in April 2026, show that unmarried men are between 68% [2] and 70% [1] more likely to develop cancer than their married counterparts.

Women in the same category faced an even higher disparity. The study found that unmarried women are about 83% more likely to develop cancer than married women [2].

Experts believe these disparities stem from the lifestyle advantages often associated with marriage. "Social factors such as marital status may be an under-recognized determinant of cancer risk," said a University of Miami researcher [4].

While the exact biological mechanism remains unclear, the researchers pointed toward the stability provided by a partner. Caleb Bond said that married people generally are happier, more content, and better off in life, which may contribute to the lower risk [1].

The study suggests that married individuals may have better access to healthcare, and more consistent adherence to healthy lifestyles, due to the emotional and financial support of a spouse [1, 4].

“Unmarried men are between 68% and 70% more likely to develop cancer than their married counterparts.”

This research highlights the intersection of sociology and oncology, suggesting that isolation or the lack of a domestic partner can manifest as physical vulnerability. By identifying marital status as a potential health determinant, medical providers may be able to better identify high-risk patients who lack traditional social support systems and prioritize them for preventative screenings.