Hormone replacement therapy use among women in the U.S. nearly doubled between January 2017 and April 2026 [1].
This surge in prescriptions reflects a shifting approach to managing menopausal symptoms and long-term health in the U.S. As more patients seek these treatments, the trend highlights a change in how medical providers and patients weigh the benefits and risks of hormonal interventions.
According to data released by Epic Research, the use of these therapies saw approximately a 100% increase [1] during this period. The tracking began in January 2017 and continued through April 2026 [2].
HRT is typically used to alleviate symptoms associated with menopause, such as hot flashes and night sweats. The data indicates a substantial rise in the number of menopausal patients receiving these prescriptions over the last nine years.
The growth in usage suggests a broader trend in women's healthcare, as patients increasingly advocate for symptom relief and preventative care. The data from Epic Research provides a quantitative look at how these medical patterns have evolved across the country, marking a distinct departure from previous decades of more cautious prescribing.
“Hormone replacement therapy use among women in the United States nearly doubled”
The doubling of HRT usage suggests a significant shift in clinical practice and patient demand regarding menopausal care. This trend may indicate a move away from the restrictive prescribing patterns seen in earlier decades, as clinicians and patients potentially reassess the risk-benefit ratio of hormone therapies for midlife health.



