The World Health Organization has released a guide detailing the laboratory process of breast biopsies to help patients understand diagnostic procedures.

Accurate biopsy processing is critical because these samples provide the primary evidence needed to distinguish between benign lumps and malignant tumors. This ensures patients receive the correct treatment plan based on precise cellular analysis.

Biomedical scientist Yolly said the workflow inside a laboratory setting begins with the extraction of tissue samples, which are then handled according to strict safety procedures to prevent contamination. Once the tissue is collected, it undergoes fixation—a chemical process that preserves the biological structure of the cells for examination under a microscope.

These laboratory steps are essential for detecting breast cancer and other abnormalities. While the procedure can cause anxiety for patients, data indicates that approximately 80% [1] of breast cancer biopsies result in benign findings. This high percentage of non-cancerous results highlights the necessity of the biopsy as a screening tool to rule out malignancy.

The physical and emotional toll of these procedures can be significant. For example, pop star Jessie J said she underwent five [2] breast biopsies during her own health battle.

Laboratory professionals said the integrity of the tissue sample depends on the speed and precision of the fixation process. If the sample is not handled correctly, the diagnostic accuracy may be compromised. The WHO video aims to demystify these clinical steps to reduce patient fear and improve health literacy regarding oncology diagnostics.

Approximately 80% of breast cancer biopsies are benign.

The emphasis on laboratory transparency by the WHO reflects a broader effort to reduce patient anxiety surrounding diagnostic procedures. By highlighting that the vast majority of biopsies are benign, health organizations aim to encourage early detection while managing the psychological impact of multiple invasive tests.